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Concomitant usage of oxycodone HCl with CYP3A4 inducers or discontinuation of the CYP3A4 inhibitor could minimize oxycodone plasma concentrations, lower opioid efficacy or, possibly, bring on a withdrawal syndrome inside of a patient who had designed physical dependence to oxycodone.one)]. Instruct patients not to share oxycodone HCl with Some othe